VIP is supplied as a catalogued research material in 5 mg.

“VIP” alone does not establish the terminal form. Aviptadil is the mature 28-residue C-terminally amidated peptide, while a separate free-acid record differs by elemental composition, mass, CAS and database identity. The batch sequence and terminal group must be confirmed before registry fields are selected [1–3].

Chemical properties and registry information

Registry values apply only to the specific molecular entity, sequence, termini and material form. Batch records take precedence over family-level literature identifiers.

Vasoactive Intestinal Peptide is a 28-amino acid neuropeptide that belongs to the glucagon/secretin superfamily. It is widely distributed in the central and peripheral nervous systems.

Research background and published evidence

Published research

Appropriate contexts include VPAC1 and VPAC2 receptor binding, cAMP signalling, peptide-fragment structure–activity work and analytical discrimination of amidated versus free-acid material. PACAP-family comparisons require their own exact standards [1–3].

Current scientific understanding

Results for aviptadil, free-acid VIP, PACAP or a separately manufactured medicinal formulation are not automatically interchangeable. Receptor-assay observations do not establish human-use safety, efficacy or suitability for this batch.

Aviptadil/VIP has medicinal and investigational regulatory history.

Technical comparison

Quality and testing

Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.

Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.

Laboratory handling and storage

Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.

Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment and waste disposal should follow the applicable SDS and the institution’s approved procedures.

Regulatory and legal status

Sources and references

1. [1] FDA GSRS. Aviptadil substance record.
2. [2] KEGG Drug. Aviptadil record.
3. [3] Review of VIP biosynthesis and amidation.

Frequently Asked Questions

Do the CAS number and PubChem CID apply to every batch form?

Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.

What does an analytical purity result mean?

It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.

How should the material be stored and handled?

Follow the exact label, batch CoA and SDS together with the institution’s risk assessment. Use only storage and stability information linked to the exact material form and batch.